Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Statistical Measurement Statistical Measurement [Domain] Operating Lease, Liability, Current, Statement of Financial Position [Extensible List] Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration] Net realized gain on investments Realized Investment Gains (Losses) Award Timing Predetermined Award Timing Predetermined [Flag] Entity File Number Entity File Number Seralutinib In Process Research And Development Seralutinib [Member] In Process Research And Development Seralutinib Additional paid-in capital Additional Paid-in Capital [Member] Convertible Senior Notes Debt, Policy [Policy Text Block] Tabular List, Table Tabular List [Table Text Block] Leases [Abstract] Leases [Abstract] Intangible Asset, Acquired, Finite-Lived [Line Items] Intangible Asset, Acquired, Finite-Lived [Line Items] Recent Accounting Pronouncements - Adopted and Not Yet Adopted New Accounting Pronouncements, Policy [Policy Text Block] Number of significant distinct performance obligations Number Of Distinct Performance Obligations Number Of Distinct Performance Obligations Accounts payable Increase (Decrease) in Accounts Payable 98% Applicable Conversion Price Ninety Eight Percent Applicable Conversion Price [Member] Ninety Eight Percent Applicable Conversion Price [Member]. Research and development credit, net Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount Gross Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Warrants outstanding (in shares) Class of Warrant or Right, Outstanding Net loss per share, basic (in dollars per share) Earnings Per Share, Basic Adjustment to Compensation: Adjustment to Compensation [Axis] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Commercial paper Commercial Paper [Member] Contract With Customer, Liability [Rollforward] Contract With Customer, Liability Rollforward [Abstract] Contract With Customer, Liability Rollforward Common stock available for issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Stock-based compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Total gross deferred tax assets Deferred Tax Assets, Gross License Agreement License Agreement [Member] License agreement. Revenue from contracts with collaborators Revenue from Contracts with Collaborators [Member] Revenue from Contracts with Collaborators Schedule of Segment Reporting Information Schedule of Segment Reporting Information, by Segment [Table Text Block] Issuance of common stock for restricted stock units vested (in shares) Stock Issued During Period, Shares, Restricted Stock Award, Net of Forfeitures Issuance of common stock pursuant to Employee Stock Purchase Plan (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Loyalty term, expiration period Revenue, Loyalty Receivable, Expiration Period Collaboration Agreement, Loyalty Receivable, Expiration Period Schedule of Available for Sale Investments by Security Type Schedule of Available-for-Sale Securities Reconciliation [Table Text Block] Adjustment to Compensation, Amount Adjustment to Compensation Amount Other assets Increase (Decrease) in Other Operating Assets Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Non-cancelable Lease Agreement Entered in August 2018 Non-cancelable Lease Agreement Entered in August 2018 [Member] Non-cancelable Lease Agreement Entered in August 2018 Development and regulatory milestone payments Business Combination Contingent Consideration Development And Regulatory Milestone Payments Payable Business combination, contingent consideration, development and regulatory milestone payments, payable. Shares issuable upon exercise of stock options Employee Stock Options Share-Based Payment Arrangement, Option [Member] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Research and Development Research and Development Expense, Policy [Policy Text Block] Effective Income Tax Rate Reconciliation, Percent [Abstract] Effective Income Tax Rate Reconciliation, Percent [Abstract] Antidilutive Securities Antidilutive Securities [Axis] Contract with customer, liability, fair value of equity option Contract With Customer, Liability, Fair Value Of Equity Option Contract With Customer, Liability, Fair Value Of Equity Option Total stockholders' equity (deficit) Beginning balance Ending balance Equity, Attributable to Parent Insider Trading Policies and Procedures [Line Items] Share-based payment arrangement, expense Total stock-based compensation expense Share-Based Payment Arrangement, Expense Schedule of Property and Equipment, Net Property, Plant and Equipment [Table Text Block] Common stock, shares authorized (in shares) Common Stock, Shares Authorized Issuance of common stock in connection with a private offering, net of offering costs (in shares) Issuance of common stock (in shares) Stock Issued During Period, Shares, New Issues Current assets Assets, Current [Abstract] Total liabilities and stockholders' equity (deficit) Liabilities and Equity Foreign Currency Foreign Currency Transactions and Translations Policy [Policy Text Block] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Shares Subject to Options Outstanding, Shares Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] LIABILITIES AND STOCKHOLDERS' EQUITY (DEFICIT) Liabilities and Equity [Abstract] California State and Local Jurisdiction [Member] Other income (expense) Other Nonoperating Income (Expense) [Abstract] Cover [Abstract] Cover [Abstract] Money market funds Cash and Cash Equivalents, Fair Value Disclosure Other Deferred Tax Assets, Other Maximum Maximum [Member] General and administrative General and Administrative Expense [Member] Leased area Leasee, Operating Lease, Leased Area Leasee, Operating Lease, Leased Area Accounting Policies [Abstract] Accounting Policies [Abstract] Schedule of Gross Future Minimum Annual Rental Commitments Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Schedule of IPR&D Expense In Process Research And Development Expenses [Table Text Block] In process research and development expenses. Nonvested shares under restricted stock grants Restricted Stock Restricted Stock [Member] Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Debt Instrument [Line Items] Debt Instrument [Line Items] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Concentrations of Credit Risk and Off-Balance Sheet Risk Off-Balance-Sheet Credit Exposure, Policy [Policy Text Block] Revenue from PH-ILD research and development costs subject to reimbursement PH-ILD Research And Development Services, Expenses Subject To Reimbursement [Member] PH-ILD Research And Development Services, Expenses Subject To Reimbursement Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Pay vs Performance Disclosure [Line Items] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Present value of lease payments Total operating lease liability Operating Lease, Liability Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Tranche Two Tranche Two [Member] Tranche two. Licenses, Asset Acquisitions and Contingent Consideration Business Combination [Text Block] Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Long-term convertible senior notes Long Term Convertible Senior Notes Long-term convertible senior notes. Loss before provision (benefit) for income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Entity Shell Company Entity Shell Company Schedule of Long-term Debt Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Patent Costs Legal Costs, Policy [Policy Text Block] Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Schedule of Performance Stock Unit Activity Share-Based Payment Arrangement, Performance Shares, Activity [Table Text Block] Variable Interest Entity [Table] Variable Interest Entity [Table] Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] In process research and development Research and Development Asset Acquired Other than Through Business Combination, Writeoff, Net Of Reversal Research and Development Asset Acquired Other than Through Business Combination, Writeoff, Net Of Reversal Company Selected Measure Amount Company Selected Measure Amount 2028 Lessee, Operating Lease, Liability, to be Paid, Year Three Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Name Measure Name Schedule of Amount of Net Loss Before Taxes Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] U.S. loss before taxes Income (Loss) from Continuing Operations before Income Taxes, Domestic Operating lease liabilities Current portion of operating lease liabilities (included as a component of accrued expenses and other current liabilities) Operating Lease, Liability, Current Nontaxable or nondeductible items Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent [Abstract] Document Fiscal Period Focus Document Fiscal Period Focus Revenue from PH-ILD commercial costs subject to reimbursement PH-ILD Commercial, Expenses Subject To Reimbursement [Member] PH-ILD Commercial, Expenses Subject To Reimbursement Collaborative Arrangements Collaborative Arrangement, Accounting Policy [Policy Text Block] Share-based payment arrangement, option, required cancellation percentage Share-Based Payment Arrangement, Option, Required Cancellation Percentage Share-Based Payment Arrangement, Option, Required Cancellation Percentage Award Timing Method Award Timing Method [Text Block] Award Type Award Type [Axis] Long-term contract liabilities Contract with Customer, Liability, Noncurrent Net carrying amount Long-Term Debt Total assets Assets Effect of exchange rate changes on revenue Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Commercial efforts contribution, percentage Revenue, Performance Obligation, Commercial Efforts Contribution, Percentage Revenue, Performance Obligation, Commercial Efforts Contribution, Percentage Stock-Based Compensation Share-Based Payment Arrangement [Policy Text Block] Trading Symbol Trading Symbol 2029 Lessee, Operating Lease, Liability, to be Paid, Year Four Vested (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Change in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Operating Loss Carryforwards [Table] Operating Loss Carryforwards [Table] Income Taxes Income Tax, Policy [Policy Text Block] Entity Address, City or Town Entity Address, City or Town Number of additional shares issuable in asset acquisition (in shares) Asset Acquisition, Consideration Transferred, Equity Interest, Shares Issuable, Number Of Shares Asset Acquisition, Consideration Transferred, Equity Interest, Shares Issuable, Number Of Shares Cash flows from operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Research and development credit, net Research and experimentation credits Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent Other segment items Segment Reporting, Other Segment Item, Amount Common stock vesting percentage Common Stock Vesting Percentage Common stock vesting percentage. Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Statement of Income Location, Balance Statement of Income Location, Balance [Domain] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Variable Interest Entity [Line Items] Variable Interest Entity [Line Items] Entity Emerging Growth Company Entity Emerging Growth Company Research and development Research and Development Expense (Excluding Acquired in Process Cost) Shares issuable upon exercise of warrants Warrant [Member] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Right-of-use assets obtained in exchange for lease liabilities Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Common stock were subject to outstanding options (in shares) Outstanding as of beginning balance (in shares) Outstanding as of ending balance (in shares) Shares outstanding awarded (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Repayments of debt Repayments of Lines of Credit Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Debt issuance costs Unamortized debt issuance cost Debt Issuance Costs, Net Significant Other Observable Inputs (Level 2) Fair Value, Inputs, Level 2 [Member] Document Financial Statement Error Correction [Flag] Document Financial Statement Error Correction [Flag] State income taxes, net of federal benefit Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Amount Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Business Combination Business Combination [Domain] Officer, Director, Employee Or Consultant Officer, Director, Employee Or Consultant [Member] Officer, Director, Employee Or Consultant Revenue from PAH research and development service performance obligations satisfied during reporting period Revenue from PAH research and development service performance obligation satisfied during reporting period PAH Research And Development Services, Performance Obligations Satisfied [Member] PAH Research And Development Services, Performance Obligations Satisfied Common stock, shares outstanding (in shares) Beginning balance (in shares) Ending balance (in shares) Common Stock, Shares, Outstanding Schedule of Components of Income Tax Expense (Benefit) Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Plan Name Plan Name [Axis] Property and Equipment, Net Property, Plant and Equipment, Policy [Policy Text Block] Revenue from PH-ILD research and development service performance obligations satisfied during reporting period Revenue from PH-ILD research and development service performance obligation satisfied during reporting period PH-ILD Research And Development Services, Performance Obligations Satisfied [Member] PH-ILD Research And Development Services, Performance Obligations Satisfied PEO PEO [Member] Lease Contractual Term [Domain] Lease Contractual Term [Domain] Schedule of Contractual Maturities of Available-for-sale Debt Securities Investments Classified by Contractual Maturity Date [Table Text Block] Supplemental disclosure of noncash investing and financing activities: Noncash Investing and Financing Items [Abstract] Interest income Interest income Investment Income, Interest Current: Current Income Tax Expense (Benefit), Continuing Operations [Abstract] Increase in valuation allowance Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Accrued income tax Accrued Income Taxes, Current UNITED STATES UNITED STATES Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Change in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Amount Property, plant and equipment Deferred Tax Liabilities, Property, Plant and Equipment Accumulated deficit Retained Earnings [Member] Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Income Tax Jurisdiction Income Tax Jurisdiction [Axis] Maturities of marketable securities Proceeds From Maturity Of Marketable Securities Proceeds from maturity of marketable securities. Number of Restricted Stock Units Outstanding Number of Performance Stock Units Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Schedule of Accrued Expenses and Other Current Liabilities Schedule of Accrued Liabilities [Table Text Block] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Restatement Determination Date Restatement Determination Date Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Cash and cash equivalents, at the beginning of the period Cash and cash equivalents, at the end of the period Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Income Statement [Abstract] Income Statement [Abstract] Provision (benefit) for income taxes Provision (benefit) for income taxes Income tax expense Income Tax Expense (Benefit) Commercial Planning Activities Commercial Planning Activities [Member] Commercial Planning Activities Purchase of marketable securities Payments to Acquire Marketable Securities Sale of Stock Sale of Stock [Domain] Accrued interest expense Increase (Decrease) in Interest Payable, Net Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Investment in merger option through issuance of stock Stock Issued During Period, Value, Purchase of Assets Product and Service [Domain] Product and Service [Domain] Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Axis] Total property and equipment Property, Plant and Equipment, Gross Options exercisable as of ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Business Combination [Table] Business Combination [Table] Organization, Consolidation and Presentation of Financial Statements [Abstract] Amortization of operating lease right-of-use assets Operating Lease, Right-of-Use Asset, Periodic Reduction Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Proceeds from the exercise of stock options Proceeds from Stock Options Exercised Proceeds from issuance of common stock and warrants in a private offering, net of offering costs Proceeds from Issuance of Private Placement Stockholders Equity Deficit [Table] Stockholders Equity Deficit [Table] Stockholders equity deficit. City Area Code City Area Code Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] All Trading Arrangements All Trading Arrangements [Member] Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Convertible notes, redemption percentage Debt Instrument, Redemption Price, Percentage Weighted-Average Remaining Contractual Life (in years), Options vested and expected to vest as of end of period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Accrued expenses and other current liabilities Total accrued expenses and other current liabilities Accrued Liabilities, Current Amortization Deferred Tax Assets, Goodwill and Intangible Assets Other Adjustments Effective Income Tax Rate Reconciliation, Other Adjustments, Amount Nonvested beginning balance (in shares) Nonvested ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Amount funded Proceeds from Long-Term Lines of Credit Number of licenses granted Number Of Licenses Granted Number Of Licenses Granted Schedule of Contract Liability Activity Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block] Cash flows from investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] General and administrative General and Administrative Expense Unrecognized compensation related to unvested stock option Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Stock awards granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares Effective Income Tax Rate Reconciliation [Table] Effective Income Tax Rate Reconciliation [Table] Property, plant and equipment, useful life Estimated Useful Life (in years) Property, Plant and Equipment, Useful Life Subsequent Event Subsequent Event [Member] Total lease cost Lease, Cost Effective Income Tax Rate Reconciliation [Line Items] Effective Income Tax Rate Reconciliation [Line Items] Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Schedule of Lease Costs Lease, Cost [Table Text Block] PEO Total Compensation Amount PEO Total Compensation Amount Depreciation expense Depreciation Long-term Debt, Type Long-Term Debt, Type [Axis] Options vested and expected to vest as of ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Money market funds Money Market Funds [Member] Lease Contractual Term [Axis] Lease Contractual Term [Axis] Equity Components Equity Components [Axis] Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Unrecognized Tax Benefits [Roll Forward] Unrecognized Tax Benefits [Roll Forward] Tender offer or exchange offer, percentage of shares outstanding Collaboration Agreement, Equity Option Owned By Counterparty, Tender Offer Or Exchange Offer, Percentage of Shares Outstanding Collaboration Agreement, Equity Option Owned By Counterparty, Tender Offer Or Exchange Offer, Percentage of Shares Outstanding Auditor Name Auditor Name Payments received in advance Contract With Customer, Liability, Upfront Payment Received Contract With Customer, Liability, Upfront Payment Received Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Number of reportable segments Number of Reportable Segments Lab equipment Equipment [Member] Warrants and rights outstanding, term Warrants and Rights Outstanding, Term Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Investments in Variable Interest Entities Variable Interest Entity Disclosure [Text Block] Other Performance Measure, Amount Other Performance Measure, Amount Shares Subject to Options Outstanding, Weighted Average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] U.S. Treasury and agency securities U.S Treasury and agency securities US Treasury and Government [Member] Entity Address, State or Province Entity Address, State or Province Marketable Securities Marketable Securities, Policy [Policy Text Block] Antidilutive Security, Excluded EPS Calculation [Table] Antidilutive Security, Excluded EPS Calculation [Table] Account receivable, payment term Account Receivable, Payment Term Account Receivable, Payment Term Related Party Related and Nonrelated Parties [Domain] Total current liabilities Liabilities, Current Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] Accrued research and development expenses Increase Decrease In Accrued Research And Development Expenses Amount of increase (decrease) in accrued research and development expenses. Restructuring and related cost, percentage of positions eliminated to total workforce Restructuring and Related Cost, Number of Positions Eliminated, Period Percent Individual: Individual [Axis] Vesting Vesting [Axis] Income Tax Jurisdiction Income Tax Jurisdiction [Domain] Document Annual Report Document Annual Report Research and development Research and Development Expense [Member] Additional paid-in capital Additional Paid in Capital, Common Stock Research and development fund committed Research And Development Arrangement, Contractual Obligation, Amount Committed Research And Development Arrangement, Contractual Obligation, Amount Committed Net cash provided by (used in) investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Cash paid for interest Interest Paid, Excluding Capitalized Interest, Operating Activity Document Fiscal Year Focus Document Fiscal Year Focus Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Shares of common stock, repurchase (in shares) Financial Instruments Subject to Mandatory Redemption, Settlement Terms, Number of Shares Operating lease right-of-use assets Operating Lease, Right-of-Use Asset Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Principal repayments of long-term debt Repayments of Long-Term Debt Effective Tax Rate Effective Income Tax Rate Reconciliation, Percent Section 174 capitalization Deferred Tax Asset, In-Process Research and Development Entity Interactive Data Current Entity Interactive Data Current Operating lease cost Operating Lease, Cost Decrease related to prior year positions Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions Contractual interest expense Contractual Interest Expense Contractual interest expense. Plan Name Plan Name [Domain] Award vesting rights, threshold consecutive days Share-Based Compensation Arrangement By Share-Based Payment Award, Award Vesting Rights, Threshold Consecutive Days Share-Based Compensation Arrangement By Share-Based Payment Award, Award Vesting Rights, Threshold Consecutive Days Weighted-average period of cost expects to recognize (in years) Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Exercise of stock options (in shares) Option exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Valuation allowance Deferred Tax Assets, Valuation Allowance Equity [Abstract] Equity [Abstract] Segment Information Segment Reporting Disclosure [Text Block] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Net operating losses Deferred Tax Assets, Operating Loss Carryforwards Property, Plant and Equipment, Type Long-Lived Tangible Asset [Axis] Federal Current Federal Tax Expense (Benefit) Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Development and regulatory milestone payments, due upon the initiation of a phase 3 clinical trial Business Combination Contingent Consideration Initial Phase Three Clinical Payments Payable Business Combination Contingent Consideration Initial Phase Three Clinical Payments Payable Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Fair Value, Recurring and Nonrecurring [Table] Fair Value, Recurring and Nonrecurring [Table] Leases Lessee, Leases [Policy Text Block] Additional shares of restricted stock subject to vesting restrictions (in shares) Incremental Common Shares Attributable To Restricted Stock Subject To Vesting Incremental common shares attributable to restricted stock subject to vesting. Depreciation and amortization Depreciation, Depletion and Amortization Other assets Other Assets, Noncurrent Pulmokine, Inc. Pulmokine Inc [Member] Pulmokine, Inc. Debt instrument conversion ratio Debt Instrument, Convertible, Conversion Ratio Accrued interest Interest Payable, Current Entity Central Index Key Entity Central Index Key PEO Name PEO Name Convertible notes, initial conversion price (in dollars per share) Debt Instrument, Convertible, Conversion Price Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Supplemental disclosure of cash flow information: Supplemental Cash Flow Elements [Abstract] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Statutory tax rate difference between Ireland and United States Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Amount Arrangement Duration Trading Arrangement Duration Tranche 1 Share-Based Payment Arrangement, Tranche One [Member] Volatility, maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Current contract liabilities Deferred revenue, current Contract with Customer, Liability, Current Nontaxable or nondeductible items Effective Income Tax Rate Reconciliation, Nondeductible Expense, Amount [Abstract] Segments [Axis] Segments [Axis] Class of warrant or right, exercise price of warrants or rights Exercise price of warrants (in dollars per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Convertible notes, percentage of last reported sale price of common stock Debt Instrument Convertible Conversion Last Reported Sale Price Percentage Debt instrument convertible conversion last reported sale price percentage. Auditor Information [Abstract] Auditor Information Exercise Price Award Exercise Price Entity Filer Category Entity Filer Category Local Phone Number Local Phone Number Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Unrecognized compensation related to unvested restricted stock awards Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Shares price (in USD per share) Share Price Reporting Segment Reporting Segment [Member] Reporting Segment Federal statutory income tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Subsequent Event Type [Axis] Subsequent Event Type [Axis] Equity Incentive Plans Share-Based Payment Arrangement [Text Block] ASSETS Assets [Abstract] Credit Facility [Axis] Credit Facility [Axis] Underlying Security Market Price Change Underlying Security Market Price Change, Percent Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Revenue from PAH commercial costs subject to reimbursement PAH Commercial, Expenses Subject To Reimbursement [Member] PAH Commercial, Expenses Subject To Reimbursement Vesting Vesting [Domain] Commercial milestone payments, payable Business Combination Contingent Consideration Commercial Milestone Payments Payable Business combination, contingent consideration, commercial milestone payments, payable. Debt Instrument [Axis] Debt Instrument [Axis] Forfeited/cancelled (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Fair Value Measurements and Available for Sale Investments Fair Value Disclosures [Text Block] Business Combination [Line Items] Business Combination [Line Items] Base rent Lessee, Operating Lease, Base Rent Lessee, Operating Lease, Base Rent Credit Facility [Domain] Credit Facility [Domain] Stockholders' equity (deficit) Equity, Attributable to Parent [Abstract] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Collaboration agreement, sales milestones receivable Revenue, Performance Obligation, Sales Milestones, Amount Revenue, Performance Obligation, Sales Milestones, Amount Operating sublease, annual increase percentage for base rent Lessee, Operating Lease, Base Rent Annual Increase Percentage Lessee, Operating Lease, Base Rent Annual Increase Percentage Award vesting rights, percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Entity Address, Address Line One Entity Address, Address Line One Share-based compensation arrangement by share-based payment award, additional number of shares authorized (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Additional Number of Shares Authorized Share-Based Compensation Arrangement by Share-Based Payment Award, Additional Number of Shares Authorized Accumulated other comprehensive income (loss) AOCI Attributable to Parent [Member] Interest rate Debt Instrument, Interest Rate, Stated Percentage Schedule of Contract Revenues Disaggregated by Timing of Revenue Recognition and Excludes Royalty Revenue Revenue from External Customers by Products and Services [Table Text Block] Effect of exchange rate changes on contract liabilities Contract With Customer, Liability, Effect Of Change In Exchange Rate Contract With Customer, Liability, Effect Of Change In Exchange Rate Operating lease liabilities - long-term Operating lease liabilities - long-term Operating Lease, Liability, Noncurrent Entity Voluntary Filers Entity Voluntary Filers Accrued accounting fees Accrued Accounting Fees Current Accrued accounting fees current. Business Combination, Asset Acquisition, Transaction between Entities under Common Control, and Joint Venture Formation [Abstract] Revenue from PAH research and development costs subject to reimbursement PAH Research And Development Services, Expenses Subject To Reimbursement [Member] PAH Research And Development Services, Expenses Subject To Reimbursement Fair Value as of Grant Date Award Grant Date Fair Value Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Abstract] Change in unrealized gain (loss) on marketable securities, net Noncash Investing And Financing Activities Change In Unrealized Gain On Marketable Securities Net Of Tax Noncash investing and financing activities change in unrealized gain on marketable securities net of tax. Entity Registrant Name Entity Registrant Name Proceeds from the exercise of warrants Proceeds from Warrant Exercises Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Net operating losses (“NOL”) carryforwards Operating Loss Carryforwards Revenue from sale of US license US License US License [Member] US License Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Accrued legal fees Accrued Legal Fees, Current Accrued legal fees current. Forfeited/cancelled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Options exercisable as of ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Share-based payment arrangement, nonvested award, cost not yet recognized, amount Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Commercialization activities performance, percentage Revenue, Performance Obligation, Commercialization Activities Performance, Percentage Revenue, Performance Obligation, Commercialization Activities Performance, Percentage Offering costs Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Number of securities with unrealized losses Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Interest receivable Interest Receivable, Current Founder Founder [Member] Founder. Counterparty Name [Domain] Counterparty Name [Domain] 2027 Lessee, Operating Lease, Liability, to be Paid, Year Two Number of operating segments Number of Operating Segments Exercise of warrants Stock Issued During Period, Value, Warrant Excised Stock Issued During Period, Value, Warrant Excised US License Licenses Of Intellectual Property [Member] Licenses Of Intellectual Property Shares reserved for issuance on granting of outstanding awards (in shares) Shares Reserved For Issuance On Granting Of Outstanding Awards Shares Reserved For Issuance On Granting Of Outstanding Awards Amortization of premium on investments, net of accretion of discounts Accretion (Amortization) of Discounts and Premiums, Investments Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Termination tee, number of monthly base rent Lessee, Operating Lease, Termination Fee, Number Of Months Of Base Rent Lessee, Operating Lease, Termination Fee, Number Of Months Of Base Rent Weighted- Average Remaining Contractual Life (Years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Related Party Related and Nonrelated Parties [Axis] Title Trading Arrangement, Individual Title Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Tax Credits Effective Income Tax Rate Reconciliation, Tax Credit, Percent [Abstract] Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Restatement Determination Date: Restatement Determination Date [Axis] Faheem Hasnain [Member] Faheem Hasnain Number of additional tranches Number Of Additional Tranches Number of additional tranches. 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Foreign rate differential Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent Unrecognized tax benefits that would not impact effective tax rate Unrecognized Tax Benefits That Would Not Impact Effective Tax Rate Unrecognized tax benefits that would not impact effective tax rate. Nonvested beginning balance (in dollars per share) Nonvested ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] ICFR Auditor Attestation Flag ICFR Auditor Attestation Flag Revenue: Revenues [Abstract] Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Cash equivalents, at carrying value Cash Equivalents, at Carrying Value Stock-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Tax Credits Effective Income Tax Rate Reconciliation, Tax Credit, Amount [Abstract] Accumulated other comprehensive income (loss) Accumulated Other Comprehensive Income (Loss), Net of Tax Aggregate Intrinsic Value, Options vested and expected to vest as of end of period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Financial Instruments [Domain] Financial Instruments [Domain] Total gross deferred tax liabilities Deferred Tax Liabilities, Gross Foreign Tax Jurisdiction Foreign Tax Jurisdiction [Member] Auditor Firm ID Auditor Firm ID Segments [Domain] Segments [Domain] Statement of Income Location, Balance Statement of Income Location, Balance [Axis] Non-Deductible Interest Effective Income Tax Rate Reconciliation, Nondeductible Expense, Interest, Amount Effective Income Tax Rate Reconciliation, Nondeductible Expense, Interest, Amount Foreign loss before taxes Income (Loss) from Continuing Operations before Income Taxes, Foreign Remaining borrowing capacity Line of Credit Facility, Remaining Borrowing Capacity Nonvested shares under performance stock units Performance Shares Performance Shares [Member] Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] 2019 Equity Incentive Plan Two Thousand Nineteen Equity Incentive Plan [Member] Two thousand nineteen equity incentive plan. Common stock vesting period Common Stock Vesting Period Common stock vesting period. Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Domain] Other Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Amount Commercial paper Commercial Paper, Not Included with Cash and Cash Equivalents [Member] Extension term Lessee, Operating Lease, Extension Term Lessee, Operating Lease, Extension Term Lease Agreement Entered in August 2024 Lease Agreement Entered in July 2024 [Member] Lease Agreement Entered in July 2024 Amortization of long-term debt discount and issuance costs Amortization of Debt Issuance Costs and Discounts Finite-Lived Intangible Assets by Major Class Finite-Lived Intangible Assets by Major Class [Axis] Number of warrants (in shares) Class of Warrant or Right, Number of Securities Called by Warrants or Rights Minimum Minimum Minimum [Member] Orphan Drug Credit, net Effective Income Tax Rate Reconciliation, Tax Credit, Other, Percent Less: accumulated depreciation Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Net Loss Per Share Earnings Per Share, Policy [Policy Text Block] Revenue recognition period Contract With Customer, Revenue Recognition Period Contract With Customer, Revenue Recognition Period Percentage in aggregate principal amount (not less than) Long-term Debt, Percentage In Aggregate Principal Amount Long-term Debt, Percentage In Aggregate Principal Amount Company Selected Measure Name Company Selected Measure Name Upfront payment Upfront Payment Upfront payment. Revenue Recognition Revenue [Policy Text Block] Indebtedness Debt Disclosure [Text Block] Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Accounts payable Accounts Payable, Current Cash paid for operating lease liabilities Operating Lease, Payments Deferred tax liabilities: Deferred Tax Liabilities, Net [Abstract] Increased in equity capital amount Increased In Equity Capital Amount Increased in equity capital amount. Proceeds from issuance of common stock under Employee Stock Purchase Plan Proceeds from Stock Plans Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] All Executive Categories All Executive Categories [Member] Schedule of Deferred Tax Assets and Liabilities Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Common stock, $0.0001 par value; 700,000,000 shares authorized as of December 31, 2025 and December 31, 2024; 233,677,057 shares issued and outstanding as of December 31, 2025, and 226,604,138 shares issued and outstanding as of December 31, 2024 Common Stock, Value, Issued Volatility, minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Tranche 2 Share-Based Payment Arrangement, Tranche Two [Member] Weighted average common shares outstanding, diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Segments Segment Reporting, Policy [Policy Text Block] Commitments and contingencies (Note 11) Commitments and Contingencies Aggregate fair value of stock options vested Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Total income tax expense (benefit) Current Federal, State and Local, Tax Expense (Benefit) Business Combination Business Combination [Axis] Entity Small Business Entity Small Business Payments of stock issuance costs Payments of Stock Issuance Costs Net operating losses carryforward available to offset future federal taxable income , percentage Net Operating Losses Carryforward Available To Offset Future Federal Taxable Income Percentage Net operating losses carryforward available to offset future federal taxable income , percentage. Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] State Current State and Local Tax Expense (Benefit) Document Transition Report Document Transition Report Tranche One Tranche One [Member] Tranche one. Equity option owned by chiesi Collaboration Agreement, Equity Option Owned By Counterparty, Percentage Collaboration Agreement, Equity Option Owned By Counterparty, Percentage Underlying Securities Award Underlying Securities Amount Net deferred tax asset Deferred Tax Assets, Net Equity Component Equity Component [Domain] Document Period End Date Document Period End Date PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Options forfeited/cancelled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period Income Taxes Income Tax Disclosure [Text Block] Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Chiesi Farmaceutici S.p.A And Chiesi USA, Inc. Chiesi Farmaceutici S.p.A And Chiesi USA, Inc. [Member] Chiesi Farmaceutici S.p.A And Chiesi USA, Inc. Convertible notes, percentage of conversion price Debt Instrument Convertible Conversion Price Percentage Debt instrument convertible conversion price percentage. Short-term lease cost Short-Term Lease, Cost Schedule of Reconciliation of Beginning and Ending Amounts of Unrecognized Tax Benefits, Excluding Interest and Penalties Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block] Fair value of convertible senior notes Convertible Debt, Fair Value Disclosures Amortization of debt discount Amortization of Debt Discount (Premium) Document Type Document Type Significant Unobservable Inputs (Level 3) Fair Value, Inputs, Level 3 [Member] Name Outstanding Recovery, Individual Name 2019 Employee Stock Purchase Plan Two Thousand Nineteen Employee Stock Purchase Plan [Member] Two thousand nineteen employee stock purchase plan. Product and Service [Axis] Product and Service [Axis] Business Combination, Intangible Asset, Acquired, Finite-Lived [Table] Business Combination, Intangible Asset, Acquired, Finite-Lived [Table] Total revenue Total revenue from Chiesi Collaboration Agreement Total revenue Revenue from Contract with Customer, Excluding Assessed Tax All Individuals All Individuals [Member] Long-term Debt, Type Long-Term Debt, Type [Domain] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Receivable from contracts with collaborators Increase (Decrease) in Receivables Exercise of warrants (in shares) Stock Issued During Period, Shares, Warrant Exercised Stock Issued During Period, Shares, Warrant Exercised Purchase of property and equipment Payments to Acquire Property, Plant, and Equipment Point in Time: Transferred at Point in Time [Member] Options vested and expected to vest as of ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Name Forgone Recovery, Individual Name Term of awards Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Total current assets Assets, Current Statistical Measurement Statistical Measurement [Axis] Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Options forfeited/cancelled (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price Percentage of amount increase in outstanding shares Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum Accrued compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Employee Compensation Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Purchase of common stock through payroll deductions, percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent 130% Applicable Conversion Price One Hundred Thirty Percent Applicable Conversion Price [Member] 130% Applicable Conversion Price [Member] Aggregate intrinsic value, options vested in period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Private Placement Private Placement [Member] Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Accrued research and development expenses Accrued Research And Development Expenses Accrued research and development expenses. Marketable securities Marketable Securities, Current Pre-tax Loss Income (Loss) from Continuing Operations before Income Taxes, For Tax Purposes Income (Loss) from Continuing Operations before Income Taxes, For Tax Purposes Collaboration agreement, regulatory milestones receivable Revenue, Performance Obligation, Regulatory Milestones, Amount Revenue, Performance Obligation, Regulatory Milestones, Amount 2027 Notes Two Thousand Twenty Seven Notes [Member] Two Thousand Twenty Seven Notes. Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Other comprehensive income (loss) Other comprehensive income (loss) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Current liabilities Liabilities, Current [Abstract] Research and development credit Deferred Tax Assets, Tax Credit Carryforwards, Research 2023 Equity Incentive Plan Two Thousand Twenty Three Equity Inducement Incentive Plan [Member] Two Thousand Twenty Three Equity Inducement Incentive Plan Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Total operating expenses Operating Expenses Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Risk-free interest rate, minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Long-term line of credit Long-Term Line of Credit Quoted Market Prices for Identical Assets (Level 1) Fair Value, Inputs, Level 1 [Member] Revenue from sale of licenses License and Service [Member] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Tax credits Deferred Tax Assets, Tax Credit Carryforwards Product license term Product License Term Product license term. Accrued expenses Increase (Decrease) in Accrued Liabilities Net loss per share, diluted (in dollars per share) Earnings Per Share, Diluted Exercise price (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Exercise Price Orphan Drug Credit, net Effective Income Tax Rate Reconciliation, Tax Credit, Other, Amount Capital loss Deferred Tax Assets, Capital Loss Carryforwards Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Receivable from contracts with collaborators Accounts receivable Accounts Receivable, after Allowance for Credit Loss, Current Title of 12(b) Security Title of 12(b) Security Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Aggregate Intrinsic Value, Options exercisable as of end of period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value GILTI Effective Income Tax Rate Reconciliation, GILTI, Percent Other comprehensive income (loss): Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Shares issued in transition (in shares) Sale of Stock, Number of Shares Issued in Transaction Description of Business Business Description and Basis of Presentation [Text Block] Total other income, net Nonoperating Income (Expense) Auditor Location Auditor Location Variable Interest Entity, Not Primary Beneficiary Variable Interest Entity, Not Primary Beneficiary [Member] Vesting of restricted stock (in shares) Stock Issued During Period Shares Vesting Of Restricted Stock Stock issued during period shares vesting of restricted stock. Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Net Loss Per Share Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Less than one year Debt Securities, Available-for-Sale, Current Contract liabilities Increase (Decrease) in Contract with Customer, Liability Federal Domestic Tax Jurisdiction [Member] Present value discount Lessee, Operating Lease, Liability, Undiscounted Excess Amount Number of share issued under ESPP (in shares) Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Issued Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Issued Development cost reimbursement payment Contract With Customer, Liability, Development Cost Contract With Customer, Liability, Development Cost Other Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Percent Option exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price 2017 Equity Incentive Plan Two Thousand Seventeen Equity Incentive Plan [Member] Two thousand seventeen equity incentive plan. Collaborative Arrangement and Arrangement Other than Collaborative [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Award Timing Disclosures [Line Items] Operating Loss Carryforwards [Line Items] Operating Loss Carryforwards [Line Items] Investment in merger option through issuance of stock (in shares) Stock Issued During Period, Shares, Purchase of Assets Principal amount Long-Term Debt, Gross Options granted (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Accrued compensation and benefits Employee-related Liabilities, Current Property and Equipment, Net Property, Plant and Equipment Disclosure [Text Block] Total undiscounted rent payments Lessee, Operating Lease, Liability, to be Paid Unrealized income (loss) on marketable securities OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Non-Deductible Interest Nondeductible interest Effective Income Tax Rate Reconciliation, Nondeductible Expense, Interest, Percent Effective Income Tax Rate Reconciliation, Nondeductible Expense, Interest, Percent Stockholders’ Equity (Deficit) Equity [Text Block] Net loss Net loss Segment net loss Net Income (Loss) Attributable to Parent Subsequent Event [Table] Subsequent Event [Table] Expiration Date Trading Arrangement Expiration Date Weighted-average grant date fair value (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Weighted Average Grant Date Fair Value Accrued other Other Accrued Liabilities, Current Schedule of Reconciliation of the Federal Statutory Income Tax Rate to Effective Income Tax Rate Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Timing of Transfer of Good or Service [Axis] Timing of Transfer of Good or Service [Axis] Award vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Domestic/Foreign Restructuring Impact Effective Income Tax Rate Reconciliation, Nondeductible Expense, Restructuring Charges, Percent Other Adjustments Other Effective Income Tax Rate Reconciliation, Other Adjustments, Percent Property and equipment, net Property and equipment, net Property, Plant and Equipment, Net Purchase price of each share subject to equity option, percentage of daily volume-weighted average per share price Collaboration Agreement, Equity Option Owned By Counterparty, Purchase Price, Percentage Of Common Stock's Average Per Share Price Collaboration Agreement, Equity Option Owned By Counterparty, Purchase Price, Percentage Of Common Stock's Average Per Share Price Adoption Date Trading Arrangement Adoption Date Percentage of repurchase price is equal to principal amount of convertible notes Percentage Of Repurchase Price Is Equal To Principal Amount Of Convertible Notes Percentage of repurchase price is equal to principal amount of convertible notes Weighted-Average Remaining Contractual Life (in years), Options exercisable as of end of period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term Issuance price per share (in dollars per share) Shares Issued, Price Per Share Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Proceeds from issuance of equity option pursuant to stock purchase agreement Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised Entity Current Reporting Status Entity Current Reporting Status Operating lease, term of contract Lessee, Operating Lease, Term of Contract Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Proceeds from convertible debt Proceeds from Convertible Debt Loss from operations Operating Income (Loss) Consolidated Entities [Domain] Consolidated Entities [Domain] Credit Facility Line of Credit [Member] Accumulated deficit Accumulated deficit Retained Earnings (Accumulated Deficit) Federal statutory income tax rate Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount Sales of marketable securities Proceeds From Sale Of Marketable Securities Proceeds from sale of marketable securities. Founder Shares Founder Shares [Member] Founder shares. Term Loan Term Loan [Member] Term loan. Schedule of Stock-Based Compensation Expense Reported in Condensed Consolidated Statements of Operations Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Loss on disposal of property and equipment Gain (Loss) on Disposition of Property Plant Equipment Financial Instrument [Axis] Financial Instrument [Axis] Deferred tax assets: Deferred Tax Assets, Gross [Abstract] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Executive Category: Executive Category [Axis] Operating lease liabilities Increase Decrease In Operating Lease Liabilities Increase decrease in operating lease liabilities. Over Time: Transferred over Time [Member] Stock-based compensation Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent State income taxes, net of federal benefit Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent Share-based payment arrangement, plan modification, incremental cost Share-Based Payment Arrangement, Plan Modification, Incremental Cost Current Fiscal Year End Date Current Fiscal Year End Date Ireland IRELAND Subsequent Event Type [Domain] Subsequent Event Type [Domain] Expected term (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Finite-Lived Intangible Assets, Major Class Name Finite-Lived Intangible Assets, Major Class Name [Domain] Debt instrument, redemption term, threshold trading days Debt Instrument, Redemption Term, Threshold Trading Days Debt Instrument, Redemption Term, Threshold Trading Days Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Other Deferred Tax Liabilities, Other Payables and Accruals [Abstract] Payables and Accruals [Abstract] Weighted- Average Grant Date Fair Value Weighted- Average Grant Date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Sales milestone payments, payable Business Combination Contingent Consideration Sales Milestone Payments Payable Business combination, contingent consideration, sales milestone payments, payable. Other income, net Other income, net Other Nonoperating Income (Expense) Statement [Table] Statement [Table] Restructuring and related cost, number of positions eliminated Restructuring and Related Cost, Number of Positions Eliminated Effect of exchange rate changes on cash and cash equivalents Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Significant Agreements and Contracts Collaborative Arrangement Disclosure [Text Block] Cash flows from financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Deferred loss Deferred Tax Assets, Other Loss Carryforwards Contract liability Opening balance Ending balance Contract with Customer, Liability Timing of Transfer of Good or Service [Domain] Timing of Transfer of Good or Service [Domain] Balance at beginning of the year Balance at the end of the year Unrecognized Tax Benefits Potentially dilutive securities not included from calculation of diluted net loss per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount All Adjustments to Compensation All Adjustments to Compensation [Member] Amendment Flag Amendment Flag Offering price (in dollars per share) Sale of Stock, Price Per Share Shares reserved for future issuance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Milestones accrued Business Combination, Contingency Recognized at Acquisition Date, Liability to Asset, Excess (Less), Fair Value Termination Date Trading Arrangement Termination Date Net cash provided by (used in) financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Measure: Measure [Axis] Cash and Cash Equivalents Cash and Cash Equivalents, Unrestricted Cash and Cash Equivalents, Policy [Policy Text Block] Tranche 3 Share-Based Payment Arrangement, Tranche Three [Member] Accrued consulting fees Accrued Consulting Fees Current Accrued consulting fees current. Operating lease, weighted average discount rate Operating Lease, Weighted Average Discount Rate, Percent Greater than one year Debt Securities, Available-for-Sale, Noncurrent Schedule of Interest Expense Recognized Schedule Of Interest Expense Recognized Table [Table Text Block] Schedule of interest expense recognized. Right of use asset Deferred Tax Liabilities Right Of Use Asset Deferred tax liabilities right of use asset. Property, Plant and Equipment, Type Long-Lived Tangible Asset [Domain] Schedule of Assets Measured at Fair Value on Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Weighted average common shares outstanding, basic (in shares) Weighted Average Number of Shares Outstanding, Basic Seralutinib Cost of Product and Service Sold Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Up-front, nonrefundable payment received Revenue, Performance Obligation, Upfront Nonrefundable Amount Received Revenue, Performance Obligation, Upfront Nonrefundable Amount Received Subsequent Events [Abstract] Segment Reporting [Abstract] Shares issuable upon exercise of Chiesi Equity Option Equity Option [Member] Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Debt Disclosure [Abstract] Debt Disclosure [Abstract] Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Amortization of debt issuance cost Amortization of Debt Issuance Costs Entity Tax Identification Number Entity Tax Identification Number Schedule of Net Carrying Amount of 2027 Notes Schedule Of Notes Table [Table Text Block] Schedule of liability components of notes. Unamortized debt discount Debt Instrument, Unamortized Discount Outstanding as of beginning balance (in dollars per share) Outstanding as of ending balance (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Grant of equity option pursuant to Chiesi Collaboration Agreement Adjustments To Additional Paid In Capital, Equity Option Issued Adjustments To Additional Paid In Capital, Equity Option Issued Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Purchase price of each share subject to equity option, number of trading days Collaboration Agreement, Equity Option Owned By Counterparty, Purchase Price, Number Of Trading Days Collaboration Agreement, Equity Option Owned By Counterparty, Purchase Price, Number Of Trading Days Consolidated Entities [Axis] Consolidated Entities [Axis] Award vesting rights, threshold share price (in dollars per share) Share-Based Compensation Arrangement By Share-Based Payment Award, Award Vesting Rights, Threshold Share Price Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Threshold Share Price Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Purchase price of each share subject to equity option, minimum price threshold (in dollars per share) Collaboration Agreement, Equity Option Owned By Counterparty, Minimum Purchase Price Collaboration Agreement, Equity Option Owned By Counterparty, Minimum Purchase Price Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Accrued Expenses and Other Current Liabilities Accrued Liabilities And Other Liabilities Disclosure Current [Text Block] The entire disclosure for accrued expenses, and other liabilities that are classified as current at the end of the reporting period. Employee Stock Purchase Plan Employee Stock Purchase Plan [Member] Employee stock purchase plan member. Common stock, shares issued (in shares) Common Stock, Shares, Issued Weighted average remaining lease term Operating Lease, Weighted Average Remaining Lease Term Options granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Lease liability Deferred Tax Assets Lease Liability Deferred tax assets lease liability. Use of Estimates Use of Estimates, Policy [Policy Text Block] Entity Public Float Entity Public Float Schedule of Fair Value of Stock Option Award Granted Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Interest expense Interest expense Interest Expense, Nonoperating Trading Arrangement: Trading Arrangement [Axis] Total Shareholder Return Amount Total Shareholder Return Amount Share-based payment arrangement, option, exercise price range, shares outstanding (in shares) Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding Subsequent events Subsequent Events [Text Block] Foreign currency translation Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax Insider Trading Arrangements [Line Items] Security Exchange Name Security Exchange Name Total liabilities Liabilities Stockholders Equity Deficit [Line Items] Stockholders Equity Deficit [Line Items] Stockholders equity deficit. Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Maximum borrowing capacity Line of Credit Facility, Maximum Borrowing Capacity In process research and development In Process Research and Development, Policy [Policy Text Block] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Increase related to current year positions Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions Operating expenses: Operating Expenses [Abstract] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Issuance of common stock in connection with a private offering, net of offering costs Issuance of common stock Stock Issued During Period, Value, New Issues Statement [Line Items] Statement [Line Items] Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Cash and cash equivalents Cash and Cash Equivalent Counterparty Name [Axis] Counterparty Name [Axis] Schedule of Restricted Stock Activity Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Subsequent Event [Line Items] Subsequent Event [Line Items] Convertible notes, consecutive trading days Debt Instrument, Convertible, Threshold Trading Days In process research and development expenses Total in process research and development Research And Development In Process Expenses Research And Development In Process Expenses Risk-free interest rate, maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Common stock Common Stock [Member] Vested (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period U.S. Treasury and agency securities, Commercial paper, and corporate debt securities Total Fair Value Total Debt Securities, Available-for-Sale Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Non-NEOs Non-NEOs [Member] Corporate debt securities Corporate debt securities Corporate Debt Securities [Member] Net increase (decrease) in cash and cash equivalents Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Revenue from sale of ROW license ROW License ROW License [Member] ROW License